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Iswarya Fertility Centre & Women's Hospital
99627-00000
Male Infertility

Sperm DNA Fragmentation

High levels of DNA damage in sperm reduce fertilisation rates, impair embryo development, and increase miscarriage risk even with normal semen parameters.

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Overview

Overview

High levels of DNA damage in sperm reduce fertilisation rates, impair embryo development, and increase miscarriage risk even with normal semen parameters.

Symptoms

Normal semen analysis but recurrent IVF failure
Recurrent miscarriage
Poor embryo quality despite good egg quality

Causes

1
Oxidative stress
2
Varicocele
3
Fever
4
Chemotherapy
5
Smoking
6
Age
7
Infection

How It's Diagnosed

Sperm DNA Fragmentation Index (DFI) by SCSA, SCD, or TUNEL assay
Semen analysis
Scrotal ultrasound

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Sperm DNA Fragmentation — Causes, Symptoms & Treatment | Iswarya Fertility | Iswarya Fertility